5-Amino-1MQ is a small molecule that blocks the enzyme Nicotinamide N-methyltransferase (NNMT). This enzyme changes the NAD+ salvage pathway by adding a methyl group to nicotinamide, a form of vitamin B3. When NNMT interferes, the enzyme NAMPT cannot turn nicotinamide into NMN, which is needed to create NAD+. Because NAD+ drives cell energy, this shift directly affects how the body uses fuel.
Researchers study this compound to better understand metabolism. It is a small-molecule NNMT inhibitor studied in in-vitro and animal models of adipocyte metabolism. In laboratory models, NNMT inhibition is studied in relation to NAD+ metabolism.
Scientists store 5-Amino-1MQ in a cool, dry place away from light. They follow lab safety rules whenever they handle it. It is not a food, drug, or cosmetic, and no person or animal should consume it.
This compound comes in powder form with purity above 98.5%. Researchers use it only for lab work, including in-vitro and early-stage studies. With it, they gain a reliable tool to explore metabolism, NNMT activity, and energy balance.
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